Standardization of pre‐analytical variables in plasma microparticle determination: results of the International Society on Thrombosis and Haemostasis SSC Collaborative workshop
作者： Romaric Lacroix , Coralie Judicone , Micah Mooberry , Mohamed Boucekine , Nigel S Key
DOI: 10.1111/JTH.12207
关键词: Coagulation 、 Cancer research 、 Cancer 、 Antigen 、 Bioinformatics 、 Thrombosis 、 Inflammation 、 Phosphatidylserine 、 Apoptosis 、 Medicine 、 Cell activation
摘要: Microparticles (MP) are sub-micron sized vesicles released by activated or apoptotic cells. They generally defined as 0.1 to 1 μm membrane particles that expose the anionic phospholipid phosphatidylserine (PS) and antigens representative of their cellular origin [1]. It is now well recognized MP behave vectors bioactive molecules, playing a role in blood coagulation, inflammation, cell activation cancer metastasis. In clinical practice, circulating originating from vascular cells elevated variety prothrombotic inflammatory disorders, cardiovascular diseases, autoimmune conditions, infectious diseases [1-3]. © 2013 International Society on Thrombosis Haemostasis.
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