Lyme disease in California: a novel enzootic transmission cycle of Borrelia burgdorferi

摘要: Knowledge of zoonotic transmission cycles is essential for the development effective strategies disease prevention. The enzootiology Lyme in California differs fundamentally from that reported eastern United States. Woodrats, not mice, serve as reservoir hosts, and Ixodes neotomae, a nonhuman-biting tick, maintains agent disease, Borrelia burgdorferi, enzootic cycles. western black-legged pacificus, primary vector to humans, but it appears be an inefficient maintenance vector. Isolates B. burgdorferi exhibit considerable antigenic heterogeneity, some isolates differ strikingly recovered this other geographic regions.