Chromosome constitution of adenoma and adenocarcinoma of the colon
作者： Horatio T. Enterline , Dean A. Arvan
DOI: 10.1002/1097-0142(196710)20:10<1746::AID-CNCR2820201025>3.0.CO;2-#
关键词: Chromosome 、 Trisomy 、 Adenoma 、 Adenocarcinoma 、 Pathology 、 Nondisjunction 、 Atypia 、 Hyperploidy 、 Biology 、 Abnormal chromosomes 、 Cancer research 、 Oncology
摘要: The chromosome patterns of 17 adenomas and 7 adenocarcinomas the colon were studied using a direct technique. typical showed definite abnormalities pattern. Many pseudodiploids many cells with counts 47 identified. These latter appeared due to trisomy. Nondisjunction persistence resulting abnormal stemline is postulated. Those areas histologic atypia greater hyperploidy more numerous individually chromosomes. Hyperploidy was also marked in three which whole or part villous. two groups similar markedly hyperploid aneuploid carcinomas studied. Two poorly differentiated much less than remaining five better adenocarcinomas.
sci-hub.se 参考文章(21)
William H. Beierwaltes, Abdul A. Al-Saadi, Chromosomal changes in rat thyroid cells during iodine depletion and repletion. Cancer Research. ,vol. 26, pp. 676- 688 ,(1966)
David Cox, Chromosome constitution of nephroblastomas Cancer. ,vol. 19, pp. 1217- 1224 ,(1966) , 10.1002/1097-0142(196609)19:9<1217::AID-CNCR2820190907>3.0.CO;2-I
H STICH, Mosaic composition of preneoplastic lesions and malignant neoplasms Experimental Cell Research. ,vol. 9, pp. 277- 285 ,(1963) , 10.1016/0014-4827(63)90271-4
Resa Wakonig-Vaartaja, James A. Kirkland, A correlated chromosomal and histopathologic study of pre-invasive lesions of the cervix Cancer. ,vol. 18, pp. 1101- 1112 ,(1965) , 10.1002/1097-0142(196509)18:9<1101::AID-CNCR2820180910>3.0.CO;2-U
A. I. Spriggs, M. M. Boddington, C. M. Clarke, Chromosomes of Human Cancer Cells BMJ. ,vol. 2, pp. 1431- 1435 ,(1962) , 10.1136/BMJ.2.5317.1431
N. B. Atkin, M. C. Baker, Chromosomes in Carcinoma of the Cervix BMJ. ,vol. 1, pp. 522- 523 ,(1965) , 10.1136/BMJ.1.5433.522-C
P.S. Moorhead, P.C. Nowell, W.J. Mellman, D.M. Battips, D.A. Hungerford, Chromosome preparations of leukocytes cultured from human peripheral blood Experimental Cell Research. ,vol. 20, pp. 613- 616 ,(1960) , 10.1016/0014-4827(60)90138-5
N. B. Atkin, B. M. Richards, Clinical Significance of Ploidy in Carcinoma of Cervix: Its Relation to Prognosis BMJ. ,vol. 2, pp. 1445- 1446 ,(1962) , 10.1136/BMJ.2.5317.1445
S. Makino, M.S. Sasaki, T. Fukuschima, TRIPLOID CHROMOSOME CONSTITUTION IN HUMAN CHORIONIC LESIONS The Lancet. ,vol. 284, pp. 1273- 1275 ,(1964) , 10.1016/S0140-6736(64)92741-2
E.L. Socolow, E. Engel, Linda Mantooth, J.B. Stanbury, CHROMOSOMES OF HUMAN THYROID TUMORS. Cytogenetic and Genome Research. ,vol. 3, pp. 394- 413 ,(1964) , 10.1159/000129829