Potential target sites to modulate vascular endothelial dysfunction: Current perspectives and future directions

作者: Pitchai Balakumar , Tajpreet Kaur , Manjeet Singh

DOI: 10.1016/J.TOX.2007.12.011

关键词: PharmacologyCirculatory systemVascular smooth muscleProinflammatory cytokineEndotheliumVasodilationBlood vesselEndocrinologyInternal medicineNitric oxideEndothelial dysfunctionMedicineToxicology

摘要: … a critical role in the development of endothelial dysfunction. Vascular endothelial dysfunction is a hallmark for various cardiovascular disorders such as hypertension, atherosclerosis, …

参考文章(229)
T P Degenhardt, J W Baynes, S R Thorpe, CHEMICAL MODIFICATION OF PROTEINS BY METHYLGLYOXAL Cellular and Molecular Biology. ,vol. 44, pp. 1139- 1145 ,(1998)
Fu-hai LI, Wei XIA, Ai-wu LI, Cui-fen ZHAO, Ruo-peng SUN, Inhibition of rho kinase attenuates high flow induced pulmonary hypertension in rats. Chinese Medical Journal. ,vol. 120, pp. 22- 29 ,(2007) , 10.1097/00029330-200701010-00005
Cui-Qing Liu, Li-Min Lu, Yu Huang, [Effects of ACE2-Ang 1-7-Mas axis on blood vessel]. Progress in physiology. ,vol. 38, pp. 43- ,(2007)
Ulf Simonsen, Edgaras Stankevicius, Egidijus Kevelaitis, Enrikas Vainorius, [Role of nitric oxide and other endothelium-derived factors]. Medicina-lithuania. ,vol. 39, pp. 333- 341 ,(2003)
Csaba Szabó, Pál Pacher, Zsuzsanna Zsengellér, Anne Vaslin, Katalin Komjáti, Rita Benkö, Min Chen, Jon G. Mabley, Márk Kollai, Angiotensin II-mediated endothelial dysfunction: role of poly(ADP-ribose) polymerase activation. Molecular Medicine. ,vol. 10, pp. 28- 35 ,(2004) , 10.2119/2004-00001.SZABO
Mariarosaria Bucci, Jean-Philippe Gratton, Radu Daniel Rudic, Lisette Acevedo, Fiorentina Roviezzo, Giuseppe Cirino, William C Sessa, None, In vivo delivery of the caveolin-1 scaffolding domain inhibits nitric oxide synthesis and reduces inflammation Nature Medicine. ,vol. 6, pp. 1362- 1367 ,(2000) , 10.1038/82176
Bart Staels, Wolfgang Koenig, Aïda Habib, Régine Merval, Marilyne Lebret, Inés Pineda Torra, Philippe Delerive, Abdessamad Fadel, Giulia Chinetti, Jean-Charles Fruchart, Jamila Najib, Jacques Maclouf, Alain Tedgui, Activation of human aortic smooth-muscle cells is inhibited by PPARα but not by PPARγ activators Nature. ,vol. 393, pp. 790- 793 ,(1998) , 10.1038/31701
Y Kanda, Y Watanabe, Adrenaline increases glucose transport via a Rap1-p38MAPK pathway in rat vascular smooth muscle cells British Journal of Pharmacology. ,vol. 151, pp. 476- 482 ,(2007) , 10.1038/SJ.BJP.0707247
Nathalie Filippa, Carol L. Sable, Chantal Filloux, Brian Hemmings, Emmanuel Van Obberghen, Mechanism of Protein Kinase B Activation by Cyclic AMP-Dependent Protein Kinase Molecular and Cellular Biology. ,vol. 19, pp. 4989- 5000 ,(1999) , 10.1128/MCB.19.7.4989