Physico-chemical requirements for cellular uptake of pAntp peptide. Role of lipid-binding affinity.

作者: Guillaume Drin , Martine Mazel , Philippe Clair , Danièle Mathieu , Michel Kaczorek

DOI: 10.1046/J.1432-1327.2001.01997.X

关键词: Cell membranePlasma protein bindingPeptideLipid bilayerLiposomeEndocytosisBiochemistryPhospholipid BindingCircular dichroismChemistry

摘要: … measured by flow cytometry. Furthermore, we determined the fraction of internalized peptide … Fluorescence spectra analysis showed a blue-shift in maximum fluorescence between free (…

参考文章(35)
Anne Scheller, Johannes Oehlke, Burkhard Wiesner, Margitta Dathe, Eberhard Krause, Michael Beyermann, Mathias Melzig, Michael Bienert, Structural requirements for cellular uptake of α-helical amphipathic peptides Journal of Peptide Science. ,vol. 5, pp. 185- 194 ,(1999) , 10.1002/(SICI)1099-1387(199904)5:4<185::AID-PSC184>3.0.CO;2-9
Ehud Gazit, Anita Boman, Hans G. Boman, Yechiel Shai, Interaction of the mammalian antibacterial peptide cecropin P1 with phospholipid vesicles. Biochemistry. ,vol. 34, pp. 11479- 11488 ,(1995) , 10.1021/BI00036A021
Katsumi Matsuzaki, Magainins as paradigm for the mode of action of pore forming polypeptides Biochimica et Biophysica Acta. ,vol. 1376, pp. 391- 400 ,(1998) , 10.1016/S0304-4157(98)00014-8
Margus Pooga, Ursel Soomets, Mattias Hällbrink, Andres Valkna, Külliki Saar, Khadijeh Rezaei, Ulrika Kahl, Jing-Xia Hao, Xiao-Jun Xu, Zsuzsanna Wiesenfeld-Hallin, Tomas Hökfelt, Tamas Bartfai, Ülo Langel, Cell penetrating PNA constructs regulate galanin receptor levels and modify pain transmission in vivo. Nature Biotechnology. ,vol. 16, pp. 857- 861 ,(1998) , 10.1038/NBT0998-857
Gerhard Schwarz, Stefan Stankowski, Vincenzo Rizzo, Thermodynamic analysis of incorporation and aggregation in a membrane: application to the pore-forming peptide alamethicin. Biochimica et Biophysica Acta. ,vol. 861, pp. 141- 151 ,(1986) , 10.1016/0005-2736(86)90412-8
Daniele Derossi, Sophie Calvet, Alain Trembleau, Alié Brunissen, Gérard Chassaing, Alain Prochiantz, Cell Internalization of the Third Helix of the Antennapedia Homeodomain Is Receptor-independent Journal of Biological Chemistry. ,vol. 271, pp. 18188- 18193 ,(1996) , 10.1074/JBC.271.30.18188
Thomas Pomorski, Andreas Herrmann, Alain Zachowski, Philippe F. Devaux, Peter Müllery, Rapid determination of the transbilayer distribution of NBD-phospholipids in erythrocyte membranes with dithionite. Molecular Membrane Biology. ,vol. 11, pp. 39- 44 ,(1994) , 10.3109/09687689409161028
William C. Wimley, Trevor P. Creamer, Stephen H. White, Solvation Energies of Amino Acid Side Chains and Backbone in a Family of Host−Guest Pentapeptides Biochemistry. ,vol. 35, pp. 5109- 5124 ,(1996) , 10.1021/BI9600153