Proliferation of rat intraspinal Schwann cells following tellurium intoxication

作者: J. P. Hammang , S. F. Worth , I. D. Duncan , S. A. Gilmore

DOI: 10.1007/BF00689602

关键词: Central nervous systemImmunocytochemistryCell growthSchwann cellSpinal cordImmunologyMyelinThymidinePopulationPathologyBiology

摘要: A stable population of intraspinal Schwann cells, which developed follwing early postnatal irradiation the spinal cord, was challenged by addition tellurium (Te) to diet beginning at 30 days age. cells incorporating [3H]thymidine were identified 1 μm autoradiographs and conventional electron microscopy adjacent thin sections. Autoradiographs areas with cell myclination showed extensive labelling in Te-fed animals. In contrast, control animals not fed Te little evidence labelled cells. These data indicate that environment show a proliferative response presence rat's diet, as do their normal extraspinal milieu.

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