Orbitomedial prefrontal cortical projections to hypothalamus in the rat

摘要: A previous study in the rat revealed that distinct orbital and medial prefrontal cortical (OMPFC) areas projected to specific columns of midbrain periaqueductal gray region (PAG). This used anterograde tracing techniques define projections hypothalamus arising from same OMPFC regions. In addition, injections retrograde tracers were made into different PAG examine connections between hypothalamic regions upon by The most extensive patterns termination seen after injection tracer prelimbic infralimbic (PL/IL) ventral (VO/MO) cortices. Projections rostral PL/IL VO/MO targeted rostrocaudal extent lateral hypothalamus, as well perifornical, dorsal posterior areas. caudal terminated within including dorsomedial nucleus There also perifornical contrast, it was found anterior cingulate (AC), dorsolateral (DLO), agranular insular (AId) cortices restricted AC areas, whereas DLO AId hypothalamus. indirectly, means columns, many fields. context our findings, these data indicate that, both macaque, parallel but circuits interconnect with regions, columns. J. Comp. Neurol. 432:307‐328, 2001. © 2001 Wiley-Liss, Inc.