MeCP2 attenuates cardiomyocyte hypoxia/reperfusion-induced injury via regulation of the SFRP4/Wnt/β-catenin axis.
作者： Yudong Mu , Mengying He , Tao Zhang , Nan Li
DOI: 10.1080/1354750X.2021.1903999
关键词: MECP2 、 Cell cycle 、 Cell biology 、 Heart failure 、 SFRP4 、 Hypoxia (medical) 、 Oxidative stress 、 Chemistry 、 Wnt signaling pathway 、 Catenin
摘要: … 2 (MeCP2) is closely associated with heart failure, but its role in I/R injury remains unclear. The purpose of this study was to explore the role and underling mechanism of MeCP2 in …
sci-hub.st 参考文章(43)
Nikolaos Mellios, Danielle A Feldman, Steven D Sheridan, Jacque PK Ip, Showming Kwok, Stephen K Amoah, Bess Rosen, Brian A Rodriguez, Benjamin Crawford, Radha Swaminathan, Stephanie Chou, Yun Li, Mark Ziats, Carl Ernst, Rudolf Jaenisch, Stephen J Haggarty, Mriganka Sur, MeCP2-regulated miRNAs control early human neurogenesis through differential effects on ERK and AKT signaling. Molecular Psychiatry. ,vol. 23, pp. 1051- 1065 ,(2018) , 10.1038/MP.2017.86
Sabine Lagger, John C. Connelly, Gabriele Schweikert, Shaun Webb, Jim Selfridge, Bernard H. Ramsahoye, Miao Yu, Chuan He, Guido Sanguinetti, Lawrence C. Sowers, Malcolm D. Walkinshaw, Adrian Bird, MeCP2 recognizes cytosine methylated tri-nucleotide and di-nucleotide sequences to tune transcription in the mammalian brain. PLOS Genetics. ,vol. 13, ,(2017) , 10.1371/JOURNAL.PGEN.1006793
, , The Crucial Role of DNA Methylation and MeCP2 in Neuronal Function. Genes. ,vol. 8, pp. 141- ,(2017) , 10.3390/GENES8050141
L Y Zhao, D D Tong, M Xue, H L Ma, S Y Liu, J Yang, Y X Liu, B Guo, L Ni, L Y Liu, Y N Qin, L M Wang, X G Zhao, C Huang, MeCP2, a target of miR-638, facilitates gastric cancer cell proliferation through activation of the MEK1/2-ERK1/2 signaling pathway by upregulating GIT1. Oncogenesis. ,vol. 6, ,(2017) , 10.1038/ONCSIS.2017.60
Dörthe F. Bebensee, Karolina Can, Michael Müller, Increased Mitochondrial Mass and Cytosolic Redox Imbalance in Hippocampal Astrocytes of a Mouse Model of Rett Syndrome: Subcellular Changes Revealed by Ratiometric Imaging of JC-1 and roGFP1 Fluorescence Oxidative Medicine and Cellular Longevity. ,vol. 2017, pp. 3064016- 3064016 ,(2017) , 10.1155/2017/3064016
Brian S Johnson, Ying-Tao Zhao, Maria Fasolino, Janine M Lamonica, Yoon Jung Kim, George Georgakilas, Kathleen H Wood, Daniel Bu, Yue Cui, Darren Goffin, Golnaz Vahedi, Tae Hoon Kim, Zhaolan Zhou, Biotin tagging of MeCP2 in mice reveals contextual insights into the Rett syndrome transcriptome Nature Medicine. ,vol. 23, pp. 1203- 1214 ,(2017) , 10.1038/NM.4406
Sang-Bing Ong, Sauri Hernández-Reséndiz, Gustavo E. Crespo-Avilan, Regina T. Mukhametshina, Xiu-Yi Kwek, Hector A. Cabrera-Fuentes, Derek J. Hausenloy, Inflammation following acute myocardial infarction: Multiple players, dynamic roles, and novel therapeutic opportunities Pharmacology & Therapeutics. ,vol. 186, pp. 73- 87 ,(2018) , 10.1016/J.PHARMTHERA.2018.01.001
Chunli Wang, Fei Wang, Qing Cao, Zhen Li, Liya Huang, Shuyan Chen, The Effect of Mecp2 on Heart Failure. Cellular Physiology and Biochemistry. ,vol. 47, pp. 2380- 2387 ,(2018) , 10.1159/000491610
Sameer Arora, George A. Stouffer, Anna M. Kucharska-Newton, Arman Qamar, Muthiah Vaduganathan, Ambarish Pandey, Deborah Porterfield, Ron Blankstein, Wayne D. Rosamond, Deepak L. Bhatt, Melissa C. Caughey, Twenty Year Trends and Sex Differences in Young Adults Hospitalized With Acute Myocardial Infarction. Circulation. ,vol. 139, pp. 1047- 1056 ,(2019) , 10.1161/CIRCULATIONAHA.118.037137
Mei Yang, De‐Yan Kong, Jian‐Chang Chen, Inhibition of miR-148b ameliorates myocardial ischemia/reperfusion injury via regulation of Wnt/β-catenin signaling pathway. Journal of Cellular Physiology. ,vol. 234, pp. 17757- 17766 ,(2019) , 10.1002/JCP.28401