Sustained release tablet formulation of diethylcarbamazine
作者： S.K. Baveja , K.V.Ranga Rao , Amarjit Singh
DOI: 10.1016/0378-5173(84)90165-0
关键词: DIETHYLCARBAMAZINE CITRATE 、 Pharmacology 、 Urinary excretion 、 Sodium carboxymethylcellulose 、 Anthelmintic 、 Diethylcarbamazine 、 Sustained Release Tablet 、 Pharmaceutical technology 、 Chemistry 、 Dosage form
摘要: Abstract Sodium carboxymethylcellulose was successfully used in formulating a sustainedrelease tablet dosage form of diethylcarbamazine citrate, drug choice against human filariasis. The formulation containing DECC:NaCMC (1:7) found to be most suitable. Urinary excretion studies normal subjects using this showed steady-state levels DEC for about 12 h. Tablets prepared according the had stable shelf-life over 2 years.
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