Cleft type receptors with catalytic activity in amide deuteration

作者: Mercedes Crego , César Raposo , Ma Luisa Mussons , Ma Cruz Caballero , Joaquín R. Morán

DOI: 10.1016/S0040-4039(00)73198-4

关键词: KetoneChemistryCarboxylic acidMedicinal chemistryEnzyme catalysisHydrogen bondAmideCatalysisReceptorStereochemistry

摘要: Abstract Cleft type receptors have been prepared with a significant activity in amide deuteration. Charge-transfer and hydrogen bonds seems to be responsible for the catalytic activity.

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