作者: Mercedes Crego , César Raposo , Ma Luisa Mussons , Ma Cruz Caballero , Joaquín R. Morán
DOI: 10.1016/S0040-4039(00)73198-4
关键词: Ketone 、 Chemistry 、 Carboxylic acid 、 Medicinal chemistry 、 Enzyme catalysis 、 Hydrogen bond 、 Amide 、 Catalysis 、 Receptor 、 Stereochemistry
摘要: Abstract Cleft type receptors have been prepared with a significant activity in amide deuteration. Charge-transfer and hydrogen bonds seems to be responsible for the catalytic activity.