Orally administrable delivery device

作者： Joseph Gross , John Gerard Kelly

DOI:

关键词: Current (fluid) 、 Aqueous solution 、 Electrode 、 Body orifice 、 Chemical engineering 、 Membrane 、 Electrolyte 、 Electronic circuit 、 Biomedical engineering 、 Active ingredient 、 Chemistry

摘要: An orally administrable delivery device (10) comprising a housing (11) with walls of water-permeable material and having first chamber (13) adapted to receive an active ingredient, orifice (15) through which the ingredient is expelled from under pressure in liquid form second (14) containing two spaced-apart electrodes (16, 17) part electric circuit closed upon ingress aqueous ionic solution (14), such that potential difference set up between current flows resulting generation gas at electrode (16), once generated acting on displaceable membrane (12) compress expel for progressive gastrointestinal tract. The (16) forms by electrolyte (the solution), allowing controlled and, thereby,