Methods for preparing t-cells for cell therapy
作者： Michael Har-Noy
DOI:
关键词: Cell therapy 、 Nanotechnology 、 Biomedical engineering 、 Materials science
摘要: T-cells are generated with enhanced immunostimulatory capabilities for use in self therapy treatment protocols, by utilizing a biodegradable device support that has one or more agents reactive to T-cell surface moieties. The devices mixed the sufficiently so cross-link T-cells’ moieties and deliver signal enhance capabilities.
lens.org参考文章(202)
E. Donnall Thomas, Rainer Storb, Reginald A. Clift, Alexander Fefer, F. Leonard Johnson, Paul E. Neiman, Kenneth G. Lerner, Harold Glucksberg, C. Dean Buckner, Bone-Marrow Transplantation New England Journal of Medicine. ,vol. 292, pp. 832- 843 ,(1975) , 10.1056/NEJM197504172921605
Dmitry I. Gabrilovich, Sorena Nadaf, Jadranko Corak, Jay A. Berzofsky, David P. Carbone, Dendritic cells in antitumor immune responses. II. Dendritic cells grown from bone marrow precursors, but not mature DC from tumor-bearing mice, are effective antigen carriers in the therapy of established tumors. Cellular Immunology. ,vol. 170, pp. 111- 119 ,(1996) , 10.1006/CIMM.1996.0140
John D. Roback, Edmund K. Waller, Christopher D. Hillyer, A method of transplantation using chemotherapy-treated allogeneic cells that enhance immune responses without graft versus host disease ,(2001)
S Kasakura, [A role for T-helper type 1 and type 2 cytokines in the pathogenesis of various human diseases]. The Japanese journal of clinical pathology. ,vol. 46, pp. 915- 921 ,(1998)
R Kaneko, S Goto, S Sato, M Ito, M Sato, S Takeuchi, Impaired production of Th1 cytokines and increased frequency of Th2 subsets in PBMC from advanced cancer patients. Anticancer Research. ,vol. 18, pp. 3951- 3955 ,(1998)
M W Büchler, M Schilling, H Friess, J Kunz, H G Beger, N Funk, Treatment of advanced pancreatic cancer with mistletoe: results of a pilot trial. Anticancer Research. ,vol. 16, pp. 915- 920 ,(1996)
Richard Champlin, Issa Khouri, Steven Kornblau, Frank Marini, Paolo Anderlini, Naoto T. Ueno, Jeffrey Molldrem, Sergio Giralt, Allogeneic hematopoietic transplantation as adoptive immunotherapy. Induction of graft-versus-malignancy as primary therapy. Hematology-oncology Clinics of North America. ,vol. 13, pp. 1041- 1057 ,(1999) , 10.1016/S0889-8588(05)70108-8
Mark L. Saxton, Dan L. Longo, Holly E. Wetzel, Henry Tribble, W. Gregory Alvord, Larry W. Kwak, Arnold S. Leonard, Claudio Dansky Ullmann, Brendan D. Curti, Augusto C. Ochoa, Adoptive Transfer of Anti-CD3–Activated CD4+ T Cells Plus Cyclophosphamide and Liposome-Encapsulated Interleukin-2 Cure Murine MC-38 and 3LL Tumors and Establish Tumor-Specific Immunity Blood. ,vol. 89, pp. 2529- 2536 ,(1997) , 10.1182/BLOOD.V89.7.2529
H Tilg, E Trehu, MB Atkins, CA Dinarello, JW Mier, Interleukin-6 (IL-6) as an anti-inflammatory cytokine: induction of circulating IL-1 receptor antagonist and soluble tumor necrosis factor receptor p55 Blood. ,vol. 83, pp. 113- 118 ,(1994) , 10.1182/BLOOD.V83.1.113.113
David N. Bell, Truman Wong, Methods for the selective expansion of lymphocytes by in vitro cultivation ,(1998)