C. fumago chloroperoxidase is also a dehaloperoxidase: oxidative dehalogenation of halophenols.

摘要: We have examined the H2O2-dependent oxidative dehalogenation of 2,4,6-trihalophenols and p-halophenols catalyzed by Caldariomyces fumago chloroperoxidase (CCPO). CCPO is significantly more robust than other peroxidases can function under harsher reaction conditions, so its ability to dehalogenate halophenols could lead use as a bioremediation catalyst for aromatic reactions. Optimal catalysis occurred acidic conditions (100 mM potassium phosphate solution, pH 3.0). UV−visible absorption spectroscopy, high-performance liquid chromatography, gas chromatography/mass spectrometry clearly identified oxidized product CCPO-catalyzed corresponding 2,6-dihalo-1,4-benzoquinones. This has previously been reported two His-ligated heme-containing (see Osborne, R. L.; Taylor, L. O.; Han, K. P.; Ely, B.; Dawson, J. H. Biochem. Biophys. Res. Commun. 2004, 324, 1194−1198), but this first e...