Treg suppressive activity involves estrogen-dependent expression of programmed death-1 (PD-1)

作者: M. J. Polanczyk , C. Hopke , A. A. Vandenbark , H. Offner

DOI: 10.1093/INTIMM/DXL151

关键词: EstrogenEstrogen receptorInternal medicineCo-stimulationBiologyEndocrinologyReceptorRegulatory T cellCell biologyFOXP3IntracellularAutoimmunity

摘要: … striking differences in the PD-1 expression level in FoxP3+ cells (Tregs) obtained from wild-type (… , the majority of PD-1 expression was within the intracellular compartment of Tregs (23). …

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