Chill coma in the locust, Locusta migratoria, is initiated by spreading depolarization in the central nervous system

摘要: The ability of chill-sensitive insects to function at low temperatures limits their geographic ranges. They have species-specific below which movements become uncoordinated prior entering a reversible state neuromuscular paralysis. In spite decades research, in recent years has focused on muscle function, the role neural mechanisms determining chill coma is unknown. Spreading depolarization (SD) phenomenon that causes shutdown integrating centres central nervous system. We investigated SD process locust, Locusta migratoria . used thermolimit respirometry and electromyography whole animals extracellular intracellular recording techniques semi-intact preparations characterize events during chilling. show chill-induced system mechanism underlying critical thermal minimum for coordinated movement locusts. This finding will be important understanding how adapt acclimate changing environmental temperatures.