Common Misconceptions About Lyme Disease
作者： John J. Halperin , Phillip Baker , Gary P. Wormser
DOI: 10.1016/J.AMJMED.2012.10.008
关键词: Borrelia burgdorferi 、 Institute of medicine 、 Zoonosis 、 Lyme disease 、 Diagnostic tools 、 MEDLINE 、 Medicine 、 Intensive care medicine 、 Scientific evidence 、 Immunology 、 Bannwarth syndrome
摘要: Lyme disease, infection with Borrelia burgdorferi, is a focally endemic tick-transmitted zoonosis. During the 3 decades since responsible spirochete was identified, series of misconceptions and misunderstandings have become widely prevalent, leading to frequent misdiagnosis inappropriate treatment. Persistent concern reliability available diagnostic tools, signs symptoms nervous system involvement, appropriate choice duration antimicrobial therapy, curability infection, cause that may persist in some patients after Concern about disparate perspectives led Institute Medicine review subject. In this article we principal misconceptions, discussing their origins best currently scientific evidence related each one.
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aldf.com参考文章(51)
ALLEN C. STEERE, Erythema Chronicum Migrans and Lyme Arthritis Annals of Internal Medicine. ,vol. 86, pp. 685- 698 ,(1977) , 10.7326/0003-4819-86-6-685
Mark S. Klempner, Controlled trials of antibiotic treatment in patients with post-treatment chronic Lyme disease. Vector-borne and Zoonotic Diseases. ,vol. 2, pp. 255- 263 ,(2002) , 10.1089/153036602321653842
Fabio Tavora, Allen Burke, Ling Li, Teri J. Franks, Renu Virmani, Postmortem confirmation of Lyme carditis with polymerase chain reaction. Cardiovascular Pathology. ,vol. 17, pp. 103- 107 ,(2008) , 10.1016/J.CARPATH.2007.03.004
Monica E. Embers, Stephen W. Barthold, Juan T. Borda, Lisa Bowers, Lara Doyle, Emir Hodzic, Mary B. Jacobs, Nicole R. Hasenkampf, Dale S. Martin, Sukanya Narasimhan, Kathrine M. Phillippi-Falkenstein, Jeanette E. Purcell, Marion S. Ratterree, Mario T. Philipp, Persistence of Borrelia burgdorferi in Rhesus Macaques following Antibiotic Treatment of Disseminated Infection PLoS ONE. ,vol. 7, pp. e29914- ,(2012) , 10.1371/JOURNAL.PONE.0029914
David C. Zoschke, Lymphoproliferative Responses to Borrelia burgdorferi in Lyme Disease Annals of Internal Medicine. ,vol. 114, pp. 285- 289 ,(1991) , 10.7326/0003-4819-114-4-285
Robert A. Kalish, Gail McHugh, John Granquist, Barry Shea, Robin Ruthazer, Allen C. Steere, Persistence of immunoglobulin M or immunoglobulin G antibody responses to Borrelia burgdorferi 10-20 years after active Lyme disease. Clinical Infectious Diseases. ,vol. 33, pp. 780- 785 ,(2001) , 10.1086/322669
J. Oksi, J. Nikoskelainen, H. Hiekkanen, A. Lauhio, M. Peltomaa, A. Pitkäranta, D. Nyman, H. Granlund, S.-A. Carlsson, I. Seppälä, V. Valtonen, M. Viljanen, Duration of antibiotic treatment in disseminated Lyme borreliosis: a double-blind, randomized, placebo-controlled, multicenter clinical study European Journal of Clinical Microbiology & Infectious Diseases. ,vol. 26, pp. 571- 581 ,(2007) , 10.1007/S10096-007-0340-2
J. J. Halperin, E. L. Logigian, M. F. Finkel, R. A. Pearl, Practice parameters for the diagnosis of patients with nervous system Lyme borreliosis (Lyme disease) Neurology. ,vol. 46, pp. 619- 627 ,(1996) , 10.1212/WNL.46.3.619
Travis J. Bench, Allen Jeremias, David L. Brown, Matrix metalloproteinase inhibition with tetracyclines for the treatment of coronary artery disease. Pharmacological Research. ,vol. 64, pp. 561- 566 ,(2011) , 10.1016/J.PHRS.2011.05.002
Liz M Leite, Antônio Germano G Carvalho, Pollyanna LF Tavares Ferreira, Igor Xavier Pessoa, Danilo O Gonçalves, Amanda de Araújo Lopes, Jean Guilherme dos Santos Góes, Victor Costa de Castro Alves, Luzia Kalyne AM Leal, Gerly Anne Brito, Glauce SB Viana, None, Anti-inflammatory properties of Doxycycline and Minocycline in experimental models: an in vivo and in vitro comparative study Inflammopharmacology. ,vol. 19, pp. 99- 110 ,(2011) , 10.1007/S10787-011-0077-5