Mechanism of 'inappropriate' sinus tachycardia. Role of sympathovagal balance.

作者: C A Morillo , G J Klein , R K Thakur , H Li , M Zardini

DOI: 10.1161/01.CIR.90.2.873

关键词: Sinus tachycardiaHeart rateAtrial tachycardiaSupine positionInappropriate sinus tachycardiaElectrical conduction system of the heartTachycardiaAnesthesiaChronotropicMedicine

摘要: BACKGROUND"Inappropriate" sinus tachycardia (IST) is an uncommon and poorly defined atrial characterized by inappropriate exaggerated acceleration of heart rate with "normal" P wave. The mechanism this unknown. purpose the present study was to determine role autonomic balance in genesis IST.METHODS AND RESULTSSix female patients aged 23 38 years IST 10 age- sex-matched control subjects were assessed following function tests: (1) sympathovagal node calculating LF/HF (low frequency/high frequency) ratio using power spectral analysis both supine position after minutes head-up tilt 60 degrees, (2) cardiovagal reflex cold face test (CFT), (3) beta-adrenergic sensitivity as determined isoproterenol dose-response curves chronotropic dose 25 (CD25), (4) intrinsic (IHR) bloc...

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