Combined application of low-intensity pulsed ultrasound and functional electrical stimulation accelerates bone-tendon junction healing in a rabbit model

作者: Jianzhong Hu , Jin Qu , Daqi Xu , Tao Zhang , Ling Qin

DOI: 10.1002/JOR.22505

关键词: Quantitative computed tomographyRabbit modelTendonFibrocartilageBiomedical engineeringQuadriceps MusclesSurgeryMedicineFunctional electrical stimulationBone mineral contentLow-intensity pulsed ultrasoundOrthopedics and Sports Medicine

摘要: The objective of this study was to elucidate the combined use low-intensity pulsed ultrasound (LIPUS) and functional electrical stimulation (FES) on patella–patellar tendon (PPT) junction healing using a partial patellectomy model in rabbits. LIPUS delivered continuously starting day 3 postoperative until week 6. FES applied quadriceps muscles induce tensile force repaired PPT 5 days per for 6 weeks since 7 postoperatively. Forty rabbits with were randomly divided into four groups: control, alone, LIPUS + FES groups. At 12, complexes harvested histology, radiographs, peripheral quantitative computed tomography, biomechanical testing. There better remodeling newly formed bone fibrocartilage zone three treatment groups compared control group. and/or treatments significantly increased area mineral content new bone. failure load ultimate strength complex also highly improved More higher properties showed group or alone Early later additive effects accelerating healing. © 2013 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. J Orthop Res 32:204–209, 2014.

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