Targeting optimal time for hyperbaric oxygen therapy following carbon monoxide poisoning for prevention of delayed neuropsychiatric sequelae: A retrospective study.
作者： Shu-Chen Liao , Yan-Chiao Mao , Kun-Ju Yang , Kuo-Cheng Wang , Li-Ying Wu
DOI: 10.1016/J.JNS.2018.11.025
关键词: Logistic regression 、 Retrospective cohort study 、 Carbon monoxide poisoning 、 Emergency medicine 、 Medical record 、 Glasgow Coma Scale 、 Medicine 、 Emergency department 、 Hyperbaric medicine 、 Outpatient clinic
摘要: Abstract Objectives Delayed neuropsychiatric sequelae (DNS) are serious complications of carbon monoxide poisoning; disorders can occur within a few days recovery from acute poisoning. Hyperbaric oxygen therapy (HBOT) has been the main treatment (CO) poisoning and was recommended as choice for CO by American Undersea Medical Society Tenth European Consensus Conference on Medicine Underwater Baromedical Society. However, optimal timing commencing HBOT in patients with remains unknown. We therefore conducted retrospective study an attempt to target time DNS prevention. Methods A review patient files/medical records all admitted Emergency Department Linkou Chang-Gung Memorial Hospital, Taiwan between January 1, 2009 December 31, 2015. total 279 who received were eligible further detection. defined presence one following neurological, cognitive, or psychological that documented medical record during hospital stay outpatient clinic follow-up at least 6 months. multivariable logistic regression analysis employed identify potential determinants after receiving receiver operating characteristic (ROC) curve used analyse influence duration exposure development. Results Glasgow coma score Conclusions identified several predictors HBOT. Multivariable regressions revealed longer HBOT, loss consciousness, multiple victims independent should be performed early possible preferably 22.5 h
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