Investigation of the biomechanical environment within the optic nerve head by finite element modelling

作者: Ian A. Sigal , John G. Flanagan , Inka Tertinegg , C. Ross Ethier

DOI: 10.1016/B978-008044046-0.50442-5

关键词: ScleraAnatomyMaterials scienceLaminaHead (vessel)Deformation (mechanics)Finite element methodOptic nerveGlaucomatous optic neuropathyBiomedical engineering

摘要: Publisher Summary This chapter aims at evaluating the role of mechanical stresses in development glaucomatous optic neuropathy. It uses methods, such as a simplified “generic” model nerve head was created—consisting sclera, pre-laminar neural tissue, lamina cribrosa, and post-laminar tissue. The biomechanical environment is simulated using finite element method, results are compared with experimental measurements pressure-induced deformation tissues. result obtained from method that computed pattern anterior retinal surface similar to measured experimentally changes topography function pressure differences between parameterized normal eyes. qualitative correspondence model; topographic change, change consistent assumption stress related

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