Telomeres and telomerase in normal and malignant haematologic cells.
作者： Brian Leber , Silvia Bacchetti
DOI: 10.3109/10428199609045709
关键词: Telomerase RNA component 、 Molecular biology 、 Germline 、 Cell division 、 Telomerase 、 Telomere 、 Biology 、 DNA 、 Cancer research 、 Telomerase reverse transcriptase 、 Telomere-binding protein
摘要: Telomeres, the ends of eukaryotic chromosomes, are structural and functional units composed of proteins and repetitive DNA sequences. Telomeres protect the ends of …
informaworld.com参考文章(55)
W. E. Wright, D. Brasiskyte, M. A. Piatyszek, J. W. Shay, Experimental elongation of telomeres extends the lifespan of immortal x normal cell hybrids. The EMBO Journal. ,vol. 15, pp. 1734- 1741 ,(1996) , 10.1002/J.1460-2075.1996.TB00519.X
CM Counter, J Gupta, CB Harley, B Leber, S Bacchetti, Telomerase activity in normal leukocytes and in hematologic malignancies. Blood. ,vol. 85, pp. 2315- 2320 ,(1995) , 10.1182/BLOOD.V85.9.2315.BLOODJOURNAL8592315
A.M. Olovnikov, A theory of marginotomy: The incomplete copying of template margin in enzymic synthesis of polynucleotides and biological significance of the phenomenon Journal of Theoretical Biology. ,vol. 41, pp. 181- 190 ,(1973) , 10.1016/0022-5193(73)90198-7
C. B. Harley, R. Effros, I. Uchida, H. Vaziri, Xiaoming Zhu, Lan Wei, D. Cohen, F. Schächter, Loss of telomeric DNA during aging of normal and trisomy 21 human lymphocytes American Journal of Human Genetics. ,vol. 52, pp. 661- 667 ,(1993)
C M Counter, F M Botelho, P Wang, C B Harley, S Bacchetti, Stabilization of short telomeres and telomerase activity accompany immortalization of Epstein-Barr virus-transformed human B lymphocytes. Journal of Virology. ,vol. 68, pp. 3410- 3414 ,(1994) , 10.1128/JVI.68.5.3410-3414.1994
C.M. Counter, A.A. Avilion, C.E. LeFeuvre, N.G. Stewart, C.W. Greider, C.B. Harley, S. Bacchetti, Telomere shortening associated with chromosome instability is arrested in immortal cells which express telomerase activity. The EMBO Journal. ,vol. 11, pp. 1921- 1929 ,(1992) , 10.1002/J.1460-2075.1992.TB05245.X
T. M. Bryan, A. Englezou, J. Gupta, S. Bacchetti, R. R. Reddel, Telomere elongation in immortal human cells without detectable telomerase activity. The EMBO Journal. ,vol. 14, pp. 4240- 4248 ,(1995) , 10.1002/J.1460-2075.1995.TB00098.X
Kazuma Ohyashiki, Atsuhiro Iwabuchi, Ken Kawakubo, Toshikatsu Fujimura, Keisuke Toyama, Takashi Shimamoto, Junko H. Ohyashiki, Telomere Shortening Associated with Disease Evolution Patterns in Myelodysplastic Syndromes Cancer Research. ,vol. 54, pp. 3557- 3560 ,(1994)
T de Lange, L Shiue, R M Myers, D R Cox, S L Naylor, A M Killery, H E Varmus, Structure and variability of human chromosome ends. Molecular and Cellular Biology. ,vol. 10, pp. 518- 527 ,(1990) , 10.1128/MCB.10.2.518
Mieczyslaw A. Piatyszek, Silvia Bacchetti, Carol W. Greider, Jerry W. Shay, Ariel A. Avilion, Jyothi Gupta, Human telomerase RNA and telomerase activity in immortal cell lines and tumor tissues Cancer Research. ,vol. 56, pp. 645- 650 ,(1996)