Efficacy and tolerability of finasteride 1 mg in men aged 41 to 60 years with male pattern hair loss

摘要: A 24-month double-blind, randomized, placebo-controlled, parallel-group, multicenter study of 424 men was conducted to determine the efficacy and tolerability finasteride 1 mg on hair growth/loss in aged 41 60 years with mild-to-moderate, predominantly vertex male pattern loss. Efficacy evaluated by review global photographs scalp taken at baseline Months 6, 12, 18, 24 patient self-assessments investigator clinical assessments change from collected 24. Safety analyses included assessment laboratory adverse experiences, including sexual experiences. Analysis photographic data showed significant improvement growth for group compared those taking placebo beginning Month 6 (p < 0.001) maintained through 0.001). Results self-assessment were consistent assessment. Finasteride improved loss results seen placebo. Improvement evident months treatment continued months. Treatment generally well tolerated.