Effects of unilateral cervical vagotomy on antral endocrine cells in mouse.
作者： M el-Salhy , Åke Danielsson , Bi-Feng Qian , H Axelsson , A Shalaby
DOI: 10.14670/HH-14.705
关键词: Enteroendocrine cell 、 Immunohistochemistry 、 Endocrinology 、 Serotonin 、 Chromogranin A 、 Antrum 、 Vagus nerve 、 Gastrin 、 Vagotomy 、 Internal medicine 、 Medicine
摘要: The present study was carried out to investigate the effect of unilateral cervical vagotomy on antral endocrine cells in mouse. Fifty-four mice were randomly divided into three groups, 18 each, for left or right vagotomy, sham operation as controls. animals sacrificed 2, 4, and 8 weeks after operation, respectively. Chromogranin-, gastrin/CCK-, serotonin-, somatostatin-cells detected by immunohistochemistry quantitated computerised image analysis. results showed that number chromogranin-cells decreased both vagotomized 4 remained at same level weeks. numbers gastrin-, serotonin- did not change vagotomy. However, gastrin- whereas no found serotonincells. Endocrine with vacuolated cytoplasm pyknotic nuclei also observed during course time. alteration this seemed be dynamic depended observation time well denervated branches vagus nerve. This may explain, least partially contradictory obtained earlier different investigators.
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sci-hub.st 参考文章(16)
Lindsey Inman, S.Kwon Lee, Ifat A. Shah, Richard C. Thirlby, Mark Feldman, Effect of truncal vagotomy on parietal cell mass and antral gastrin cell mass in dogs. Gastroenterology. ,vol. 99, pp. 1581- 1592 ,(1990) , 10.1016/0016-5085(90)90461-9
P. Facer, A.E. Bishop, R.V. Lloyd, B.S. Wilson, R.J. Hennessy, J.M. Polak, Chromogranin: A newly recognized marker for endocrine cells of the human gastrointestinal tract Gastroenterology. ,vol. 89, pp. 1366- 1373 ,(1985) , 10.1016/0016-5085(85)90657-2
G.E. Holle, E. Buck, L. Pradayrol, E. Wünsch, F. Holle, Behavior of somatostatin-immunoreactive cells in the gastric mucosa before and after selective proximal vagotomy and pyloroplasty in treatment of gastric and duodenal ulcers Gastroenterology. ,vol. 89, pp. 736- 745 ,(1985) , 10.1016/0016-5085(85)90567-0
M. EL-SALHY, Application of computer image analysis in endocrine cell quantification. Histochemical Journal. ,vol. 29, pp. 249- 256 ,(1997) , 10.1023/A:1026458027425
Bifeng Qian, Åke Danielsson, Magdy El-Salhy, Vagal regulation of the gastrointestinal neuroendocrine system. Scandinavian Journal of Gastroenterology. ,vol. 31, pp. 529- 540 ,(1996) , 10.3109/00365529609009124
Herbert Koop, Margareta Frank, Simone Kuly, Rüdiger Nold, Rolf Eissele, Gudrun Rager, Josef Rüschoff, Matthias Rothmund, Rudolf Arnold, Gastric argyrophil (enterochromaffin-like), gastrin, and somatostatin cells after proximal selective vagotomy in man. Digestive Diseases and Sciences. ,vol. 38, pp. 295- 302 ,(1993) , 10.1007/BF01307547
MICHAEL W. MULHOLLAND, MARGARET BONSACK, JOHN P. DELANEY, Proliferation of Gastric Endocrine Cells after Vagotomy in the Rat Endocrinology. ,vol. 117, pp. 1578- 1584 ,(1985) , 10.1210/ENDO-117-4-1578
M. El-Salhy, R. Stenling, L. Grimelius, Peptidergic Innervation and Endocrine Cells in the Human Liver Scandinavian Journal of Gastroenterology. ,vol. 28, pp. 809- 815 ,(1993) , 10.3109/00365529309104014
Fernando Magallanes, Terence M. Quigley, Michael W. Mulholland, Margaret Bonsack, John P. Delaney, Antral proliferation of G cells after truncal, parietal cell, and antral vagotomy. Journal of Surgical Research. ,vol. 32, pp. 377- 381 ,(1982) , 10.1016/0022-4804(82)90116-0
Theodore Drapanas, William C. Woolverton, Jack W. Reeder, Richard L. Reed, Rudolph F. Weichert, Experiences with surgical management of acute gastric mucosal hemorrhage: a unified concept in the pathophysiology. Annals of Surgery. ,vol. 173, pp. 628- 640 ,(1971) , 10.1097/00000658-197105000-00002