Gene content evolution on the X chromosome

作者: Tatiana A Gurbich , Doris Bachtrog

DOI: 10.1016/J.GDE.2008.09.006

关键词: X hyperactivationAutosomeSex linkageBiologyX:A ratioChromosome 21Evolutionary biologyGeneticsX chromosomeChromosome 17 (human)X-inactivationDevelopmental biology

摘要: Compared with autosomes, the X chromosome shows different patterns of evolution as a result its hemizygosity in males. Additionally, inactivation during spermatogenesis can make an unfavorable location for male-specific genes. These factors help to explain why many species gene content differs from that autosomes. Indeed, mouse is enriched genes while they are depleted on Drosophila but show neither these trends mosquito. Here, we will discuss recent findings ancestral and neo-X chromosomes support sexual antagonism force shaping sex suggest selection could be driving male-biased off X.

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