Simulated vernix compositions for skin cleansing and other applications

作者: Steven B. Hoath , William L. Pickens , Martha O. Visscher

DOI:

关键词: Skin surfacesSkin cleansingVernix caseosaNormal skinBarrier functionLipid matrixSynthetic CellsChromatographyChemistry

摘要: A composition and a method of producing which simulates hydration, cleansing other properties native vernix. The contains hydrated synthetic cells in lipid matrix to provide rheological are substantially similar those vernix, may also contain proteins. In one embodiment, the cubosomes/water with up 30 % protein about 5 lipid. be used cleanse newborn skin, compromised skin surfaces, as well normal hydration/barrier function, applications.

参考文章(114)
Wael Youssef, R. Randall Wickett, Steven B. Hoath, Surface free energy characterization of vernix caseosa. Potential role in waterproofing the newborn infant Skin Research and Technology. ,vol. 7, pp. 10- 17 ,(2001) , 10.1034/J.1600-0846.2001.007001010.X
A. Mavon, H. Zahouani, D. Redoules, P. Agache, Y. Gall, Ph. Humbert, Sebum and stratum corneum lipids increase human skin surface free energy as determined from contact angle measurements: A study on two anatomical sites Colloids and Surfaces B: Biointerfaces. ,vol. 8, pp. 147- 155 ,(1997) , 10.1016/S0927-7765(96)01317-3
Wayne R. Falla, Michael Mulski, E.L. Cussler, Estimating diffusion through flake-filled membranes Journal of Membrane Science. ,vol. 119, pp. 129- 138 ,(1996) , 10.1016/0376-7388(96)00106-8
J. Bettinger, M. Gloor, C. Peter, P. Kleesz, J. Fluhr, W. Gehring, Opposing Effects of Glycerol on the Protective Function of the Horny Layer against Irritants and on the Penetration of Hexyl Nicotinate Dermatology. ,vol. 197, pp. 18- 24 ,(1998) , 10.1159/000017970
N. Nicolaides, Hwei C. Fu, M. N. A. Ansari, Gary R. Rice, The fatty acids of wax esters and sterol esters from vernix caseosa and from human skin surface lipid. Lipids. ,vol. 7, pp. 506- 517 ,(1972) , 10.1007/BF02533016
Gitte D. Nielsen, Jesper B. Nielsen, Klaus E. Andersen, Philippe Grandjean, Effects of Industrial Detergents on the Barrier Function of Human Skin International Journal of Occupational and Environmental Health. ,vol. 6, pp. 138- 142 ,(2000) , 10.1179/OEH.2000.6.2.138
Michelle M. Emery, Adelaide A. Hebert, A. Aguirre Vila-Coro, Thomas C. Prager, The relationship between skin maturation and electrical skin impedance Journal of Dermatological Science. ,vol. 2, pp. 336- 340 ,(1991) , 10.1016/0923-1811(91)90026-T
D. K. Owens, R. C. Wendt, Estimation of the surface free energy of polymers Journal of Applied Polymer Science. ,vol. 13, pp. 1741- 1747 ,(1969) , 10.1002/APP.1969.070130815
Patrick T. Spicer, Kristin L. Hayden, Matthew L. Lynch, Akua Ofori-Boateng, Janet L. Burns, Novel Process for Producing Cubic Liquid Crystalline Nanoparticles (Cubosomes) Langmuir. ,vol. 17, pp. 5748- 5756 ,(2001) , 10.1021/LA010161W