Gene regulation during development by chromatin and the Super Elongation Complex

作者: Olle Dahlberg

DOI:

关键词: Developmental biologyTranscription (biology)ChromatinRegulation of gene expressionGeneticsOrganismElongationBiology

摘要: Developmental processes are carefully controlled at the level of transcription to ensure that fertilized egg develops into an adult organism. The mechanisms controls prote ...

参考文章(127)
Man Mohan, Chengqi Lin, Erin Guest, Ali Shilatifard, Licensed to elongate: a molecular mechanism for MLL-based leukaemogenesis Nature Reviews Cancer. ,vol. 10, pp. 721- 728 ,(2010) , 10.1038/NRC2915
Marianne Stabell, Jan Larsson, Reidunn B. Aalen, Andrew Lambertsson, Drosophila dSet2 functions in H3-K36 methylation and is required for development Biochemical and Biophysical Research Communications. ,vol. 359, pp. 784- 789 ,(2007) , 10.1016/J.BBRC.2007.05.189
Bluma J. Lesch, David C. Page, Genetics of germ cell development Nature Reviews Genetics. ,vol. 13, pp. 781- 794 ,(2012) , 10.1038/NRG3294
Sheng-Hao Chao, David H. Price, Flavopiridol inactivates P-TEFb and blocks most RNA polymerase II transcription in vivo. Journal of Biological Chemistry. ,vol. 276, pp. 31793- 31799 ,(2001) , 10.1074/JBC.M102306200
Joshua C. Black, Capucine Van Rechem, Johnathan R. Whetstine, Histone Lysine Methylation Dynamics: Establishment, Regulation, and Biological Impact Molecular Cell. ,vol. 48, pp. 491- 507 ,(2012) , 10.1016/J.MOLCEL.2012.11.006
Mark Ptashne, Alexander Gann, Transcriptional activation by recruitment Nature. ,vol. 386, pp. 569- 577 ,(1997) , 10.1038/386569A0
Shima Nakanishi, Brian W Sanderson, Kym M Delventhal, William D Bradford, Karen Staehling-Hampton, Ali Shilatifard, A comprehensive library of histone mutants identifies nucleosomal residues required for H3K4 methylation. Nature Structural & Molecular Biology. ,vol. 15, pp. 881- 888 ,(2008) , 10.1038/NSMB.1454
Emma Byrne, Amanda Clare, Muhammed N Khan, Maria Liakata, Magdalena Markham, Jem Rowland, Larisa N Soldatova, Kenneth E Whelan, Michael Young, Ross D King, Andrew Sparkes, Wayne Aubrey, Towards Robot Scientists for autonomous scientific discovery Automated Experimentation. ,vol. 2, pp. 1- 11 ,(2010) , 10.1186/1759-4499-2-1
P. J. J. Robinson, D. A. Bushnell, M. J. Trnka, A. L. Burlingame, R. D. Kornberg, Structure of the Mediator Head module bound to the carboxy-terminal domain of RNA polymerase II Proceedings of the National Academy of Sciences of the United States of America. ,vol. 109, pp. 17931- 17935 ,(2012) , 10.1073/PNAS.1215241109
A. Saunders, L. J. Core, C. Sutcliffe, J. T. Lis, H. L. Ashe, Extensive polymerase pausing during Drosophila axis patterning enables high-level and pliable transcription Genes & Development. ,vol. 27, pp. 1146- 1158 ,(2013) , 10.1101/GAD.215459.113