Do calcium antagonists inhibit atherogenesis?
作者： G. Scannapieco , P. Pauletto
DOI: 10.1007/978-94-009-0731-7_45
关键词: Cholesterol diet 、 Medicine 、 In vivo 、 Calcium 、 Adverse effect 、 In vitro 、 Aortic atherosclerosis 、 Pharmacology 、 Plasma lipoprotein
摘要: In the last few years calcium antagonists have been reported to act as antiatherosclerotic agents independently from any modification of risk factors. Since these compounds no adverse effect on plasma lipoproteins profile and are effective antihypertensives, they may represent first-line drugs in this field. However, contrasting results literature antiatherogenic experimental animals, only preliminary data exist humans. This paper summarizes main vivo vitro studies so far conducted field focuses mechanisms by which exert their action.
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