Population Pharmacokinetic and Pharmacodynamic Modeling

作者: Roger Jelliffe , Alan Schumitzky , Aida Bustad , Michael Van Guilder , Xin Wang

DOI: 10.1007/978-1-4419-9216-1_12

关键词: MedicinePopulationPharmacokineticsIntensive care medicineDrugPharmacodynamicsDrug developmentPatient care

摘要: As we acquire experience with the clinical and pharmacokinetic behavior of a drug, it is very desirable to capture this its related information in form population model, then relate model effects drug or linked pharmacodynamic model. The purpose modeling thus describe our certain group patients subjects manner that will be useful for treatment future patients. This true not only patient care, but also optimize each step development, develop optimal understanding behavior, so next can taken most intelligently.

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