Transcriptional regulation of subclass 5b fimbriae

作者: Maria D Bodero , Elizabeth A Harden , George P Munson

DOI: 10.1186/1471-2180-8-180

关键词: FimbriaSubclassEnterotoxinEnterotoxigenic Escherichia coliTranscriptional regulationPlasmidVirulenceMicrobiologyBiologySmall intestine

摘要: Background Enterotoxigenic Escherichia coli (ETEC) is a major cause of infant and child mortality in developing countries. This enteric pathogen causes profuse watery diarrhea by elaborating one or more enterotoxins that intoxicate eukaryotic cells ultimately leads to loss water the intestinal lumen. Virulence also dependent upon fimbrial adhesins facilitate colonization small intestine.

参考文章(34)
Edgar C Boedeker, Vaccines for enterotoxigenic Escherichia coli: current status. Current Opinion in Gastroenterology. ,vol. 21, pp. 15- 19 ,(2005)
Gabriel E. Soto, Scott J. Hultgren, Bacterial adhesins: common themes and variations in architecture and assembly. Journal of Bacteriology. ,vol. 181, pp. 1059- 1071 ,(1999) , 10.1128/JB.181.4.1059-1071.1999
Jeffrey H Miller, Experiments in molecular genetics ,(1972)
Allan M. Maxam, Walter Gilbert, [57] Sequencing end-labeled DNA with base-specific chemical cleavages Nucleic Acids Part I. ,vol. 65, pp. 499- 560 ,(1980) , 10.1016/S0076-6879(80)65059-9
R Espejo, J Olarte, L G Zhen, M M Mathew, M A Khan, Z Sami, S Huilan, M A Ghafoor, M M Mathan, U Khin Maung, Etiology of acute diarrhoea among children in developing countries: a multicentre study in five countries. Bulletin of The World Health Organization. ,vol. 69, pp. 549- 555 ,(1991)
H Valvatne, H Sommerfelt, W Gaastra, M K Bhan, H M Grewal, Identification and characterization of CS20, a new putative colonization factor of enterotoxigenic Escherichia coli. Infection and Immunity. ,vol. 64, pp. 2635- 2642 ,(1996) , 10.1128/IAI.64.7.2635-2642.1996
A Bairoch, R Schleif, K Hofmann, M T Gallegos, J L Ramos, Arac/XylS family of transcriptional regulators. Microbiology and Molecular Biology Reviews. ,vol. 61, pp. 393- 410 ,(1997) , 10.1128/MMBR.61.4.393-410.1997
J. Caron, L. M. Coffield, J. R. Scott, A plasmid-encoded regulatory gene, rns, required for expression of the CS1 and CS2 adhesins of enterotoxigenic Escherichia coli Proceedings of the National Academy of Sciences of the United States of America. ,vol. 86, pp. 963- 967 ,(1989) , 10.1073/PNAS.86.3.963
Didier Favre, Stefan Lüdi, Michael Stoffel, Joachim Frey, Michael P. Horn, Guido Dietrich, Simone Spreng, Jean-François Viret, Expression of enterotoxigenic Escherichia coli colonization factors in Vibrio cholerae Vaccine. ,vol. 24, pp. 4354- 4368 ,(2006) , 10.1016/J.VACCINE.2006.02.052