Disease Risk Links to Gene Regulation

作者: E. Pennisi

DOI: 10.1126/SCIENCE.332.6033.1031

关键词: DNAGenetic associationGeneticsHuman genomeRegulation of gene expressionGeneDisease riskBiologyGenomeMultidisciplinary

摘要: Researchers have been surveying regions of the human genome to identify functions DNA outside protein-coding portions genes. They have, for example, generated genome-wide maps showing places where gene regulation occurs. Now, two teams at Biology Genomes meeting report that regulatory sites surprisingly often are spots single-nucleotide polymorphisms identified by association studies fall.

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