Difficultés de prise en charge des infections urinaires fébriles chez l’enfant vietnamien

作者: H.P. Duong , T.T. Mong Hiep , D.T. Hoang , F. Janssen , P. Lepage

DOI: 10.1016/J.ARCPED.2015.05.010

关键词:

摘要: Resume Objectifs Decrire les realites liees au diagnostic et traitement de l’infection urinaire (IU) chez enfants febriles vietnamiens, ainsi que caracteristiques cliniques la frequence des germes uropathogenes leur taux resistance. Methodes Etude prospective 28 mois realisee traites pour IU documentee dans le departement nephrologie l’hopital pediatrique Nhi-Dong 2 a Ho-Chi-Minh-Ville (Vietnam). Apres l’obtention prelevements sanguins urinaires, ont ete par ceftriaxone intraveineuse (75 mg/kg/j). 48 heures d’apyrexie, relais a pris cefixime (8 mg/kg/j) voie orale une duree totale 14 jours. L’adaptation du n’etait envisagee ne repondant pas cliniquement, sans tenir compte l’antibiogramme. Resultats Cent-quarante-trois (51 % filles) dont 80 % avaient eu premier episode d’IU avant l’âge 2 ans. Escherichia coli etait responsable IU, avec un resistance 91 % l’ampicilline 74 % cotrimoxazole. Des enterobacteries productrices β-lactamases spectre etendu (BLSE) isolees 52 % cultures. Selon l’antibiogramme, initial inapproprie 63 % cas. Conclusions E. coli est majorite l’enfant vietnamien eleve aux antibiotiques premiere ligne. La production BLSE extremement elevee. Nous proposons prise en charge plus rationnelle qu’un antibiotique empirique tenant l’emergence multiresistants.

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