The evolutionary origin of the mammalian diaphragm.

摘要: The comparatively low compliance of the mammalian lung results in an evolutionary dilemma: origin and evolution this bronchoalveolar into a high-performance gas-exchange organ high work breathing that cannot be achieved without coupled muscular diaphragm. However, despite over 400 years research respiratory biology, exclusively structure remains elusive. Here we examine basic body wall muscles vertebrates discuss mechanics costal functional significance accessory non-mammalian amniotes. We then critically diaphragm compare hypotheses on its ontogenetic phylogenetic origin. A closer look at function across various groups reveals collateral functions as visceral organizer role producing intra-abdominal pressure.