作者: Steven K. Boyd
DOI: 10.1007/978-3-540-68993-5_14
关键词: Treatment efficacy 、 Polygon mesh 、 Materials science 、 Data mining 、 Mechanical properties of biomaterials 、 Field (computer science) 、 Finite element method 、 Nanotechnology 、 Disease progress 、 Image based 、 Experimental animal
摘要: Finite element (FE) analysis is a nondestructive simulation tool that can estimate mechanical properties of biomaterials when combined with 3D imaging modalities such as micro-computed tomography. This chapter will review state-of-the-art FE methods use micro-CT to generate subject-specific models for application large cohorts experimental animal studies, and most recently patient studies. Methods used automatically meshes, recent developments improve the accuracy these well advances in acquisition material modeling incorporation constitutive into be discussed. The this technology vivo particularly exciting because it provides method noninvasively strength, provide valuable information monitoring disease progress treatment efficacy. field still early stages, there are significant opportunities advance unique combination technologies new insights strength-related issues.