Farmacogenética en investigación clínica

Bonnie A Fijal, Jeff M Hall, John S Witte, Clinical trials in the genomic era: effects of protective genotypes on sample size and duration of trial. Controlled Clinical Trials. ,vol. 21, pp. 7- 20 ,(2000) , 10.1016/S0197-2456(99)00039-2

Roland B. Stoughton, Stephen H. Friend, How molecular profiling could revolutionize drug discovery Nature Reviews Drug Discovery. ,vol. 4, pp. 345- 350 ,(2005) , 10.1038/NRD1696

Bruce Booth, Rodney Zemmel, Prospects for productivity. Nature Reviews Drug Discovery. ,vol. 3, pp. 451- 456 ,(2004) , 10.1038/NRD1384

Jeanette J. McCarthy, Rolf Hilfiker, The use of single-nucleotide polymorphism maps in pharmacogenomics Nature Biotechnology. ,vol. 18, pp. 505- 508 ,(2000) , 10.1038/75360

Alasdair Breckenridge, Klaus Lindpaintner, Peter Lipton, Howard McLeod, Mark Rothstein, Helen Wallace, Pharmacogenetics: ethical problems and solutions. Nature Reviews Genetics. ,vol. 5, pp. 676- 680 ,(2004) , 10.1038/NRG1431

Ruth March, Challenges and opportunities of pharmacogenetics in drug development. Personalized Medicine. ,vol. 3, pp. 195- 206 ,(2006) , 10.2217/17410541.3.2.195

Jeantine E Lunshof, Personalized medicine: new perspectives - new ethics? Personalized Medicine. ,vol. 3, pp. 187- 194 ,(2006) , 10.2217/17410541.3.2.187

Garret A. FitzGerald, Anticipating change in drug development: the emerging era of translational medicine and therapeutics Nature Reviews Drug Discovery. ,vol. 4, pp. 815- 818 ,(2005) , 10.1038/NRD1849

D Gurwitz, J E Lunshof, G Dedoussis, C S Flordellis, U Fuhr, J Kirchheiner, J Licinio, A Llerena, V G Manolopoulos, L J Sheffield, G Siest, F Torricelli, V Vasiliou, S Wong, Pharmacogenomics education: International Society of Pharmacogenomics recommendations for medical, pharmaceutical, and health schools deans of education. Pharmacogenomics Journal. ,vol. 5, pp. 221- 225 ,(2005) , 10.1038/SJ.TPJ.6500312

E. C. Gunther, D. J. Stone, R. W. Gerwien, P. Bento, M. P. Heyes, Prediction of clinical drug efficacy by classification of drug-induced genomic expression profiles in vitro Proceedings of the National Academy of Sciences of the United States of America. ,vol. 100, pp. 9608- 9613 ,(2003) , 10.1073/PNAS.1632587100