Possible biomarkers modulating haloperidol efficacy and/or tolerability

摘要: Haloperidol (HP) is widely used in the treatment of several forms psychosis. Despite its efficacy, HP use a cause concern for elevated risk adverse drug reactions. reactions and efficacy greatly vary across subjects, indicating involvement factors mechanism action. The biomarkers that could monitor or even predict impact would be extreme importance. We reviewed elements potentially as peripheral effectiveness. Although validated biomarker still does not exist, we underlined potential findings (e.g., about cytokines, metabolites genotypic biomarkers) which pave way future research on biomarkers.