Interactions of tetracyclines with RNA
作者： Christian Berens
DOI: 10.1007/978-3-0348-8306-1_7
关键词: Protein biosynthesis 、 Peptidyl transferase 、 RNA 、 Biochemistry 、 Ternary complex 、 Ribosomal RNA 、 Hammerhead ribozyme 、 Bacteria 、 Antibiotics 、 Chemistry
摘要: The tetracyclines (Fig. 1) are secondary metabolites produced by Gram-positive bacteria from the generaStreptomycesorNocardia.They act as antibiotics and inhibit protein biosynthesis interfering with binding of aminoacyltRNA-EF-Tu-GTP ternary complex to ribosomal A-site [1].
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