Intracellular transport of mouse kidney β-glucuronidase induced by gonadotrophin

摘要: 1. The response of renal β-glucuronidase with time to the injection gonadotrophin was investigated in each submicrosomal fraction rough and smooth microsomal fractions mouse kidney homogenate. 2. increase activity appeared initially membranes fraction, 24h after injection. 3. Afterwards newly synthesized enzyme contents subsequently found reaching a maximum concentration this at 72h. 4. At juncture, decrease observed whereas lysosomal had reached its value. 5. time-course appearance stimulation suggests that site membrane-bound ribosomes is transferred across membrane into cisternae endoplasmic reticulum, then transported lysosomes via reticulum. 6. properties β-glucuronidases were compared.