The impact of aortic endografts on renal function.

作者: Jean-Marc Alsac , Christopher K. Zarins , Maarit A. Heikkinen , John Karwowski , Frank R. Arko

DOI: 10.1016/J.JVS.2005.02.024

关键词: Blood pressureAneurysmDialysisFixation (histology)Prospective cohort studyRenal functionEndovascular aneurysm repairMedicineAbdominal aortic aneurysmSurgery

摘要: Objective To determine the impact on late postoperative renal function of suprarenal and infrarenal fixation endografts used to treat abdominal aortic aneurysm (AAA). Methods Retrospective analysis 277 patients treated from 2000 2003 with three different at two clinical centers. Five dialysis for preoperative chronic failure were excluded. Group IF 135 an device (Medtronic AneuRx) was compared group SF 137 a (106 Cook Zenith 31 Medtronic Talent). Renal evaluated by calculating latest creatinine clearance (CrCl) using Cockcroft formula. Patients who developed >20% decrease in CrCl considered have significantly impaired function. Results There no significant differences patient age, sex, size, risk factors, dose intra- contrast, or baseline (IF: 69.3 mL/min, SF: 71.7 P = .4). Follow-up time 12.2 months same both groups. decreased during follow-up period groups mL/min 61.7 .3), rate −10.9%, −9.5%, .2) not between The number n=35 [25.9%], n=41 [29.9%], .46). However, magnitude impairment greater (SF: −39%) those −31%, .005). This degree due identifiable CrCl. No these series required dialysis. Conclusions Regardless type endograft used, there is 10% first year after endovascular repair. Suprarenal does seem increase likelihood impairment. Decline over repair probably multiple measures known be effective protecting kidneys should patients. Long-term measurement CrCl, along imaging regular blood pressure measurements, performed detect possible dysfunction. Prospective studies comparing versus are needed confirm results.

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