Transgenic Animals as Bioreactors for Therapeutic and Nutritional Proteins

摘要: The development of molecular “pharming” technology culminated in transgenic animals whose mammary glands were converted into bioreactors producing human proteins. This was achieved with interdigitative efforts by several branches science — biology, embryology, and protein chemistry. Protein chemistry helps to identify sequences milk proteins, biology provides the tools for isolation genetic regulatory elements that target gene expression tissue, embryology is critical introduction novel genes embryos from which are derived. An important focus current investigation field biotechnology comes our accumulating understanding switches context complex chromatin.