Aspartyl-tRNA synthetases
作者： John D. Mendlein , Kristi Helen Piehl , Ying Ji Buechler , Chi-Fang Wu , Ryan Andrew Adams
DOI:
关键词: Cysteine 、 Biochemistry 、 Chemistry 、 Transfer RNA
摘要: The present invention provides aspartyl-tRNA synthetase derived proteins (DRS polypeptides) with altered cysteine content, compositions comprising the same, and methods of using such polypeptides for treating or diagnosing a variety conditions. DRS have immunomodulatory properties, exhibit improved activity stability.
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