Solvent-Controlled Oxidative Cyclization for Divergent Synthesis of Highly Functionalized Oxetanes and Cyclopropanes
作者： Yang Ye , Chen Zheng , Renhua Fan
DOI: 10.1021/OL9012102
关键词: Molecule 、 Oxidative cyclization 、 Organic chemistry 、 Stereoisomerism 、 Iodosobenzene 、 Chemistry 、 Catalysis 、 Solvent 、 Adduct 、 Divergent synthesis
摘要: An efficient solvent-controlled oxidative cyclization of Michael adducts malonates with chalcones the combination iodosobenzene and tetrabutylammonium iodide is reported. Highly functionalized oxetanes cyclopropanes were divergently synthesized in moderate to excellent yields high diastereoselectivity.
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