Assessment of Coronary Reperfusion After Thrombolysis With a Model Combining Myoglobin, Creatine Kinase–MB, and Clinical Variables
作者： Robert H. Christenson , E. Magnus Ohman , Eric J. Topol , Steven Peck , L. Kristin Newby
关键词: Creatine kinase 、 Thrombolysis 、 Myoglobin 、 Angiography 、 Cardiology 、 Myocardial infarction 、 TIMI 、 Chest pain 、 Creatine 、 Medicine 、 Internal medicine
摘要: Background Several biochemical markers have been investigated for the noninvasive assessment of reperfusion after myocardial infarction. Because myoglobin is released very soon injury and clears rapidly reperfusion, it may prove to be an excellent marker occlusion reperfusion. Methods Results We examined relation between various measures Thrombolysis In Myocardial Infarction (TIMI) flow grade in 96 patients enrolled a study front-loaded thrombolysis who underwent 90-minute angiography. also combined with models that include clinical creatine kinase–MB variables. The level measured within 10 minutes acute angiography showed best overall performance was used later analyses. Of variables examined, only time from symptom onset chest pain at discriminated among TIMI grades. Combining these showed...
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