Maternal Antibiotic Treatment Impacts Development of the Neonatal Intestinal Microbiome and Antiviral Immunity

作者: Gabriela Gonzalez-Perez , Allison L. Hicks , Tessa M. Tekieli , Caleb M. Radens , Brent L. Williams

DOI: 10.4049/JIMMUNOL.1502322

关键词: Enterococcus faecalisImmunologyImmune systemVirusCD8PregnancyAntibioticsGastrointestinal MicrobiomeAcquired immune systemBiologyMicrobiology

摘要: … Microbial colonization of the infant gastrointestinal tract (GIT) begins at birth, is shaped by the maternal microbiota, and is profoundly altered by antibiotic treatment. Antibiotic treatment …

参考文章(57)
S Matsuda, Transfer of antibiotics into maternal milk Biological research in pregnancy and perinatology. ,vol. 5, pp. 57- 60 ,(1984)
Jenny Hendriks, Loes A. Gravestein, Kiki Tesselaar, René A. W. van Lier, Ton N. M. Schumacher, Jannie Borst, CD27 is required for generation and long-term maintenance of T cell immunity Nature Immunology. ,vol. 1, pp. 433- 440 ,(2000) , 10.1038/80877
Allison M. Chung, Michael D. Reed, Jeffrey L. Blumer, Antibiotics and breast-feeding: a critical review of the literature. Pediatric Drugs. ,vol. 4, pp. 817- 837 ,(2002) , 10.2165/00128072-200204120-00006
Gregor Bedenikovic, Josh Crouse, Annette Oxenius, T-cell help dependence of memory CD8+ T-cell expansion upon vaccinia virus challenge relies on CD40 signaling European Journal of Immunology. ,vol. 44, pp. 115- 126 ,(2014) , 10.1002/EJI.201343805
Kazuo Tanaka, Sadaaki Sawamura, Tadayuki Satoh, Kiyoshi Kobayashi, Satoshi Noda, Role of the Indigenous Microbiota in Maintaining the Virus-Specific CD8 Memory T Cells in the Lung of Mice Infected with Murine Cytomegalovirus Journal of Immunology. ,vol. 178, pp. 5209- 5216 ,(2007) , 10.4049/JIMMUNOL.178.8.5209
Rong Xu, Aaron J. Johnson, Denny Liggitt, Michael J. Bevan, Cellular and Humoral Immunity against Vaccinia Virus Infection of Mice The Journal of Immunology. ,vol. 172, pp. 6265- 6271 ,(2004) , 10.4049/JIMMUNOL.172.10.6265
Luis J. Sigal, Shane Crotty, Raul Andino, Kenneth L. Rock, Cytotoxic T-cell immunity to virus-infected non-haematopoietic cells requires presentation of exogenous antigen Nature. ,vol. 398, pp. 77- 80 ,(1999) , 10.1038/18038
T. Olszak, D. An, S. Zeissig, M. P. Vera, J. Richter, A. Franke, J. N. Glickman, R. Siebert, R. M. Baron, D. L. Kasper, R. S. Blumberg, Microbial Exposure During Early Life Has Persistent Effects on Natural Killer T Cell Function Science. ,vol. 336, pp. 489- 493 ,(2012) , 10.1126/SCIENCE.1219328
Betty W. Ma, Nicholas A. Bokulich, Patricia A. Castillo, Anchasa Kananurak, Mark A. Underwood, David A. Mills, Charles L. Bevins, Routine Habitat Change: A Source of Unrecognized Transient Alteration of Intestinal Microbiota in Laboratory Mice PLoS ONE. ,vol. 7, pp. e47416- ,(2012) , 10.1371/JOURNAL.PONE.0047416