In vivo targeting of B-cell lymphoma with glycan ligands of CD22
作者： Weihsu C. Chen , Gladys C. Completo , Darren S. Sigal , Paul R. Crocker , Alan Saven
DOI: 10.1182/BLOOD-2009-12-257386
关键词: Sialic acid binding 、 Cell killing 、 Chronic lymphocytic leukemia 、 CD22 、 Lymphoma 、 Biology 、 SIGLEC 、 Molecular biology 、 Hairy cell leukemia 、 B-cell lymphoma
摘要: … To investigate this further, we tested binding against a panel of cell lines expressing human and murine siglecs, revealing that the BPC NeuAc liposomes did indeed bind to human (but …
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