Biophysical and Biochemical Properties of the p53 Protein
作者： Tapas Mukhopadhyay , Steven A. Maxwell , Jack A. Roth
DOI: 10.1007/978-3-662-22275-1_4
关键词: Cell biology 、 Cell growth 、 Transcription (biology) 、 Biochemical mechanism 、 Chemistry 、 P53 protein
摘要: The biochemical mechanism of p53 in the control cell growth is not completely understood. Considerable evidence implicates regulation gene transcription as a action controlling growth. protein does resemble factor1–5 that it has an acidic domain can transactivate reporter genesG6–12 and basic carboxyl terminal bind nonspecifically to DNA13 (Fig. 4.1).
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