Controlled mixing in microfluidic systems using bacterial chemotaxis.

作者: Min Jun Kim , Kenneth S Breuer , None

DOI: 10.1021/AC0614691

关键词: MicrofluidicsChemotaxisMixing (process engineering)BiophysicsMolecular Motor ProteinsEffective diffusion coefficientChemistryMicrochannelAnalytical chemistryDiffusion

摘要: We demonstrate the use of Escherichia coli and their chemotactic characteristics to enhance mixing in a microchannel controlled bi-directional manner. The presence chemoattractant one arm three-junction results an asymmetric increase effective diffusion coefficient extremely high molecular weight TMR-Dextran (MW 2 000 000), which rises linearly with concentration attractant from baseline value 8−42 μm2/s at 0.1 M. response repellent is similar, opposite bias.

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