Restoring Vision: Where are We with Stem Cells?

作者: Jie Zhu , Deepak A. Lamba

DOI: 10.1007/S40135-015-0078-4

关键词: Stem cellGene therapy of the human retinaRetinalMacular degenerationRetinal regenerationNeuroscienceOphthalmologyRetinaRetinal pigment epitheliumRetinitis pigmentosaMedicine

摘要: Photoreceptor degeneration leads to permanent visual loss due the lack of regenerative mechanisms in mammalian retina. This can occur defects photoreceptors as seen certain forms retinitis pigmentosa or secondary retinal pigment epithelium Leber congenital amaurosis and age-related macular degeneration. In this short review, we will cover some recent work on promoting repair either by using endogenous cells retina through cell replacement therapy.

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