RNA Interference: The Next Gene‐Targeted Medicine

作者: Andrew V. Oleinikov , Matthew D. Gray

DOI: 10.1002/9780470571224.PSE324

关键词: Gene expressionBiologyRNA interferenceRNARNA silencingComputational biologyGeneticsGeneTarget mrnaMedical researchDrug development

摘要: The newest laboratory method for modulating gene expression, RNA interference (RNAi), has gained rapid interest throughout the world of molecular research, and is being actively pursued as next “gene-targeted medicine.” RNAi a process in which double-stranded (dsRNA) directs specific degradation corresponding target mRNA. This article describes main ideas, approaches, technological directions that may guide medical researcher interested using methodologies to identify develop new drug candidates. Keywords: gene expression; RNA interference; molecular research; drug development

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