Synthesis of Novel Amino Lactose and Evaluation of Its Antioxidant Property
作者： Qing Li , Yan Feng , Guodong Gu , Zhanyong Guo
关键词: Chemical modification 、 Organic chemistry 、 Antioxidant 、 IC50 、 Derivatization 、 DPPH 、 Radical 、 Chemistry 、 Hydrogen peroxide 、 Lactose
摘要: In order to improve the bioactivity of lactose, a novel lactose derivative is designed and synthesized by introducing an amino group C-6 lactose. The in vitro antioxidant activities derivatives are assessed. It shows better scavenging activity against hydrogen peroxide (IC50<0.1mgmL(-1)), hydroxyl radicals (IC50 0.55mgmL(-1)), DPPH 0.37mgmL(-1)) than Based on this data, it reasonable propose that introduction through chemical modification significant enhance free This derivatization strategy might provide effective tool broaden utilization
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