Pulmonary artery pulsatility index predicts right ventricular failure after left ventricular assist device implantation

摘要: Background Right ventricular failure (RVF) is a major cause of morbidity and mortality after left assist device (LVAD) implantation. The pulmonary artery pulsatility index (PAPi) novel hemodynamic that predicts RVF in the setting myocardial infarction, although it has not been shown to predict LVAD Methods We performed retrospective, single-center analysis examine utility PAPi predicting RV (RVAD) implantation 85 continuous-flow recipients. multivariate logistic regression incorporating previously identified predictors placement, including clinical echocardiographic variables, determine independent effect or RVAD placement. Results In this cohort, mean was 3.4 with standard deviation 2.9. occurred 33% patients, 11% required RVAD. Multivariate analysis, adjusting for age, blood urea nitrogen (BUN), Interagency Registry Mechanically Assisted Circulatory Support profile, revealed higher independently associated reduced risk placement (odds ratio [OR], 0.30; 95% confidence interval [CI], 0.07–0.89). This relationship did change significantly when measures were added analysis. Stratifying by presence inotropes during catheterization more predictive requirement measured on (OR, 0.21; CI, 0.02–0.97) than without 0.49; 0.01–1.94). Furthermore, time from affect value (maximum time, 6 months). Receiver operating characteristic curve optimal sensitivity specificity achieved using threshold 2.0. Conclusions recipients, an predictor need support appears patients receiving affected our cohort.